The Lei Liu Group

The Lei Liu Group, Department of Chemistry, Tsinghua University. 清华大学化学系刘磊课题组

Department of Chemistry

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Research

We are developing a comprehensive method system to implement de novo chemical synthesis of any proteins found in nature or artificially designed, without limitation of the building block structure or chirality. This method system allows us to address fundamental biochemical questions, such as elucidation of how enzymes selectively making or breaking chemical bonds on complex protein substrates, and create novel functional molecules, such as synthetic protein-based self-amplification and self-replication systems.

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